Incretin analogues and co-agonists
GLP-1, GIP and glucagon receptor agonists, including the lipidated long-acting analogues and the dual and triple co-agonists.
The index applies its own acceptance specification by compound class. Every threshold is published with its reasoning and its observed failure rate. None of them is a regulatory limit and none of them is a safety threshold — a specification is a line this site drew, and these pages exist so that any PASS or FAIL chip anywhere on the site can be traced back to the decision behind it.
| Class | Compounds | Records | Purity ≥ | Water ≤ | Counter-ion ≤ | Endotoxin ≤ | Mass ± | Observed median |
|---|---|---|---|---|---|---|---|---|
| Incretin analogues and co-agonists | 12 | 2,399 | 97.0 | 8.0 | 12.0 | 5.0 | 15 | 98.66 |
| Metabolic and mitochondrial peptides | 5 | 356 | 98.0 | 9.0 | 12.0 | 5.0 | 15 | 99.26 |
| Tissue-repair and immunomodulatory peptides | 10 | 1,229 | 98.0 | 10.0 | 12.0 | 5.0 | 15 | 99.26 |
| Growth-hormone axis peptides | 13 | 1,108 | 98.0 | 9.0 | 12.0 | 5.0 | 15 | 99.00 |
| Melanocortin-receptor peptides | 5 | 509 | 98.5 | 8.0 | 10.0 | 5.0 | 15 | 99.28 |
| Hypothalamic and posterior-pituitary hormones | 5 | 134 | 98.5 | 8.0 | 10.0 | 5.0 | 15 | 99.30 |
| Neuroactive and cognitive peptides | 5 | 400 | 98.5 | 12.0 | 10.0 | 5.0 | 15 | 99.25 |
| Short bioregulator peptides | 6 | 232 | 99.0 | 12.0 | 10.0 | 5.0 | 20 | 99.06 |
| Non-peptide adjuncts | 5 | 355 | 98.5 | 10.0 | 12.0 | 5.0 | 10 | 99.17 |
GLP-1, GIP and glucagon receptor agonists, including the lipidated long-acting analogues and the dual and triple co-agonists.
Mitochondrial-derived peptides, growth-hormone fragments and peptidomimetics acting on metabolic targets.
Short to medium linear peptides marketed for tissue repair, mucosal integrity and immune modulation.
GHRH analogues, growth-hormone secretagogues, IGF-1 variants and conjugates.
Cyclic and linear melanocortin agonists, plus the kisspeptin decapeptide.
GnRH analogues and the nonapeptide hormones, several of which have pharmacopoeial monographs.
ACTH-derived and tuftsin-derived peptides, lipidated tripeptide amides and adamantylated fragments.
Di-, tri- and tetrapeptide bioregulators, plus the thiol tripeptide glutathione and the dipeptide carnosine.
Small molecules and nucleotide cofactors submitted alongside peptides. Different specification, different methods, same index.