AssayIndex

GLBI-2404-U8654

Semax · 5 mg declared · GL Biochem (Shanghai) Ltd. · manufactured 24 Apr 2024

CHARACTERISEDSHARED BULK
Lot code
GLBI-2404-U8654
Supplier
GL Biochem — GL Biochem (Shanghai) Ltd.
Compound
Semax
Compound class
Neuroactive and cognitive peptides
Declared label claim
5mg
Manufacture date
24 Apr 2024
Index quarter
2024-Q3
Independent assays
9
Laboratories involved
Janoshik, Medutest, Nordanalyt, PeptideMeter
Provenance mix
Buyer-sourced ×1 · Supplier-supplied ×8
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 9
Median purity 98.90% n=9
Spread (max − min) 1.38pp n=9
Standard deviation 0.374pp n=9
97.698.098.598.999.399.7100.1This lot (GLBI-2404-U8654)This lot (GLBI-2404-U8654): Q1 98.72, median 98.90, Q3 99.01, n=9outlier 98.19outlier 99.57n=9All SemaxAll Semax: Q1 98.65, median 99.17, Q3 99.63, n=160n=160 Purity (% area)
Figure 1. This lot's independent purity results against the whole Semax record set in the index. The vertical line is the index acceptance specification for the neuroactive and cognitive peptides class, 98.5 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 9

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2024-005282GLBI-2404-U8654Janoshik2024-Q398.887.45Supplier-supplied2MARGINAL
AX-2024-005283GLBI-2404-U8654Janoshik2024-Q398.727.1190.7Buyer-sourced2MARGINAL
AX-2024-005284GLBI-2404-U8654Medutest2024-Q398.197.50100.1Supplier-supplied2FAIL
AX-2024-005285GLBI-2404-U8654Janoshik2024-Q399.017.3094.7Supplier-supplied2MARGINAL
AX-2024-005286GLBI-2404-U8654Janoshik2024-Q399.577.40101.5Supplier-supplied2MARGINAL
AX-2024-005287GLBI-2404-U8654Nordanalyt2024-Q399.016.8198.1Supplier-supplied3MARGINAL
AX-2024-005288GLBI-2404-U8654Medutest2024-Q399.127.5496.0Supplier-supplied2MARGINAL
AX-2024-005289GLBI-2404-U8654PeptideMeter2024-Q398.657.70Supplier-supplied2MARGINAL
AX-2024-005290GLBI-2404-U8654PeptideMeter2024-Q398.907.66Supplier-supplied2MARGINAL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik498.88, 98.72, 99.01, 99.5798.9430min+0.0098.94
Medutest298.19, 99.1298.6625min+0.0898.58
Nordanalyt199.0199.0135min+0.0298.99
PeptideMeter298.65, 98.9098.7828min-0.0598.83

This lot contributes 6 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)99.598.88divergence +0.60 pp vs batch median
Total impurities (% area)0.501.12
Largest single impurity (% area)0.170.59
Water (%)not stated7.45
Counter-ion (%)not stated7.41
Peptide content (%w/w)not statednot determined
Endotoxin (EU/mg)not statednot determined
Method stated on certificateNOno method section — the result cannot be reconciled against any other
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
diketopiperazine (−18 Da)9 / 90.320.23–0.95
Met1 sulfoxide (+16 Da)9 / 90.440.11–0.60
N-acetyl semax (+42 Da)9 / 90.160.05–0.23
des-Met (−131 Da)9 / 90.150.04–0.22
Section 6

Shared-bulk links

Rule AX-R09. Where impurity fingerprints and latent composition match across companies, the index treats the material as one bulk and counts it once in aggregates.

LotSold byRoleReportsMedian purity
HJ-2603-V4363HJlinked child499.14
GLBI-2404-U8654GL Biochemthis lot998.90
Section 7

What this rollup does not establish