AssayIndex

WXT-2507-J5534

TB-500 · 2 mg declared · WuXi TIDES (WuXi AppTec Testing Division) · manufactured 18 Jul 2025

CHARACTERISED
Lot code
WXT-2507-J5534
Supplier
WXT — WuXi TIDES (WuXi AppTec Testing Division)
Compound
TB-500
Compound class
Tissue-repair and immunomodulatory peptides
Declared label claim
2mg
Manufacture date
18 Jul 2025
Index quarter
2025-Q4
Independent assays
13
Laboratories involved
Janoshik, PeptideMeter, VendorInvestigate
Provenance mix
Buyer-sourced ×3 · Supplier-supplied ×9 · Laboratory-retained ×1
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 13
Median purity 97.92% n=13
Spread (max − min) 1.56pp n=13
Standard deviation 0.423pp n=13
97.297.798.298.799.299.6100.1This lot (WXT-2507-J5534)This lot (WXT-2507-J5534): Q1 97.75, median 97.92, Q3 98.28, n=13n=13All TB-500All TB-500: Q1 98.99, median 99.47, Q3 99.81, n=356outlier 97.40outlier 97.48outlier 97.52outlier 97.62outlier 97.75outlier 97.75n=356 Purity (% area)
Figure 1. This lot's independent purity results against the whole TB-500 record set in the index. The vertical line is the index acceptance specification for the tissue-repair and immunomodulatory peptides class, 98.5 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 13

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2025-021109WXT-2507-J5534Janoshik2025-Q497.403.53Buyer-sourced2FAIL
AX-2025-021110WXT-2507-J5534PeptideMeter2025-Q497.923.28106.5Laboratory-retained2FAIL
AX-2025-021111WXT-2507-J5534Janoshik2025-Q498.303.01Supplier-supplied2FAIL
AX-2025-021112WXT-2507-J5534Janoshik2025-Q497.963.6899.1Supplier-supplied2FAIL
AX-2025-021113WXT-2507-J5534Janoshik2025-Q497.753.86100.6Buyer-sourced2FAIL
AX-2025-021114WXT-2507-J5534Janoshik2025-Q498.283.56102.4Supplier-supplied2FAIL
AX-2025-021115WXT-2507-J5534PeptideMeter2025-Q497.803.34Supplier-supplied2FAIL
AX-2025-021116WXT-2507-J5534Janoshik2025-Q497.753.41100.2Supplier-supplied2FAIL
AX-2025-021117WXT-2507-J5534Janoshik2025-Q498.203.69Supplier-supplied3FAIL
AX-2025-021118WXT-2507-J5534Janoshik2025-Q498.283.3596.4Supplier-supplied2FAIL
AX-2025-021119WXT-2507-J5534VendorInvestigate2025-Q497.623.75101.2Buyer-sourced2FAIL
AX-2025-021120WXT-2507-J5534PeptideMeter2025-Q497.483.7098.5Supplier-supplied2FAIL
AX-2025-021121WXT-2507-J5534Janoshik2025-Q498.963.82103.2Supplier-supplied2MARGINAL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik997.40, 98.30, 97.96, 97.75, 98.28, 97.75, 98.20, 98.28, 98.9698.2030min+0.0098.20
PeptideMeter397.92, 97.80, 97.4897.8028min-0.0597.85
VendorInvestigate197.6297.6232min-0.1197.73

This lot contributes 3 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)98.5497.40divergence +0.62 pp vs batch median
Total impurities (% area)not stated2.60
Largest single impurity (% area)not stated1.77
Water (%)not stated3.53
Counter-ion (%)2.95.00
Peptide content (%w/w)93.0not determined
Endotoxin (EU/mg)not statednot determined
Method stated on certificateYEScolumn, gradient and wavelength given
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
des-Gln truncate (−128 Da)13 / 130.710.14–1.77
C-terminal amide (−1 Da)13 / 130.570.23–1.54
[D-Thr]-diastereomer13 / 130.180.07–0.27
des-acetyl TB-500 (−42 Da)13 / 130.080.03–0.51
Section 7

What this rollup does not establish