Terms beginning with O
5 of 238 glossary terms.
- Open-chain form
- A cyclic peptide with its disulfide reduced, +2.016 Da. A handling artefact, resolved chromatographically, and functionally inactive.
- Oxidation
- Addition of oxygen. Methionine to sulfoxide (+15.995) then sulfone (+31.990); tryptophan to oxindole and beyond; cysteine to sulfonic acid.
- Oxidation ladder
- The series of peaks from sequential oxidation of multiple oxidisable residues: parent, mono-sulfoxide, bis-sulfoxide. Diagnostic — a single early peak with no second rung is probably something else.
- Outlier
- An observation beyond the Tukey fences at 1.5 IQR from the quartiles. Plotted individually on every box plot here rather than discarded.
- Out of specification (OOS)
- A result outside the acceptance criteria. Requires investigation before it can be invalidated; a result cannot be discarded because it is inconvenient.
see also Disulfide scrambling
see also Sulfoxide · Oxidation ladder
see also Oxidation
see also Tukey fence
see also Specification