AssayIndex

ERP-2405-P6825

NAD+ · 100 mg declared · Shanghai ERP Biotechnology Co., Ltd. · manufactured 20 May 2024

PARTIALLY CHARACTERISED
Lot code
ERP-2405-P6825
Supplier
ERP — Shanghai ERP Biotechnology Co., Ltd.
Compound
NAD+
Compound class
Non-peptide adjuncts
Declared label claim
100mg
Manufacture date
20 May 2024
Index quarter
2024-Q4
Independent assays
2
Laboratories involved
Janoshik, PeptideMeter
Provenance mix
Supplier-supplied ×2
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 2
Median purity 98.37% n=2
Spread (max − min) 0.29pp n=2
Standard deviation n<3 n=2
97.397.898.398.799.299.7100.1This lot (ERP-2405-P6825)This lot (ERP-2405-P6825): Q1 98.29, median 98.37, Q3 98.44, n=2n=2All NAD+All NAD+: Q1 98.35, median 98.88, Q3 99.38, n=48n=48 Purity (% area)
Figure 1. This lot's independent purity results against the whole NAD+ record set in the index. The vertical line is the index acceptance specification for the non-peptide adjuncts class, 97.0 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 2

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2024-004911ERP-2405-P6825Janoshik2024-Q498.229.29Supplier-supplied0PASS
AX-2024-004912ERP-2405-P6825PeptideMeter2024-Q498.519.2889.5Supplier-supplied1MARGINAL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik198.2298.2230min+0.0098.22
PeptideMeter198.5198.5128min-0.0598.56

This lot contributes 1 paired comparison to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)98.7498.22divergence +0.37 pp vs batch median
Total impurities (% area)1.261.78
Largest single impurity (% area)0.660.76
Water (%)8.89.29
Counter-ion (%)not statedN/A
Peptide content (%w/w)86.4not determined
Endotoxin (EU/mg)not statednot determined
Method stated on certificateNOno method section — the result cannot be reconciled against any other
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
ADP-ribose (−121 Da)2 / 20.650.54–0.76
nicotinamide mononucleotide (NMN, −331 Da)2 / 20.630.59–0.66
NADH (reduced, +2 Da)2 / 20.200.19–0.20
α-NAD anomer2 / 20.090.03–0.15
nicotinamide (−541 Da)2 / 20.080.07–0.08
Section 7

What this rollup does not establish