AssayIndex

QSC-2405-A6223

L-Glutathione (reduced) · 1500 mg declared · Qingdao Sigma Chemical Co., Ltd. · manufactured 09 May 2024

PARTIALLY CHARACTERISED
Lot code
QSC-2405-A6223
Supplier
QSC — Qingdao Sigma Chemical Co., Ltd.
Compound
L-Glutathione (reduced)
Compound class
Short bioregulator peptides
Declared label claim
1500mg
Manufacture date
09 May 2024
Index quarter
2024-Q3
Independent assays
2
Laboratories involved
Janoshik
Provenance mix
Supplier-supplied ×2
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 2
Median purity 99.81% n=2
Spread (max − min) 0.25pp n=2
Standard deviation n<3 n=2
96.196.897.598.298.899.5100.2This lot (QSC-2405-A6223)This lot (QSC-2405-A6223): Q1 99.74, median 99.81, Q3 99.87, n=2n=2All L-Glutathione (reduced)All L-Glutathione (reduced): Q1 98.58, median 99.00, Q3 99.57, n=122outlier 96.39n=122 Purity (% area)
Figure 1. This lot's independent purity results against the whole L-Glutathione (reduced) record set in the index. The vertical line is the index acceptance specification for the short bioregulator peptides class, 98.5 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 2

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2024-004326QSC-2405-A6223Janoshik2024-Q399.686.25101.4Supplier-supplied0PASS
AX-2024-004327QSC-2405-A6223Janoshik2024-Q399.936.66Supplier-supplied0PASS
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik299.68, 99.9399.8130min+0.0099.81

A single laboratory assayed this lot, so it contributes no paired comparison and the bias-adjusted column is a subtraction rather than a measurement.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)99.9099.68divergence +0.09 pp vs batch median
Total impurities (% area)not stated0.32
Largest single impurity (% area)not stated0.18
Water (%)5.76.25
Counter-ion (%)not statedN/A
Peptide content (%w/w)not stated93.47
Endotoxin (EU/mg)not stated2.12
Method stated on certificateYEScolumn, gradient and wavelength given
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
S-sulfonate adduct (+80 Da)2 / 20.040.04–0.05
glutathione disulfide (GSSG, +305 Da)2 / 20.030.03–0.03
γ-Glu-Cys (−57 Da)1 / 20.18
cysteinyl-glycine (−129 Da)1 / 20.06
Section 7

What this rollup does not establish