AssayIndex

QYB-2503-Y6694

Dihexa · 20 mg declared · ChinaPeptides Co., Ltd. (QYAOBIO) · manufactured 02 Mar 2025

CHARACTERISED
Lot code
QYB-2503-Y6694
Supplier
QYB — ChinaPeptides Co., Ltd. (QYAOBIO)
Compound
Dihexa
Compound class
Neuroactive and cognitive peptides
Declared label claim
20mg
Manufacture date
02 Mar 2025
Index quarter
2025-Q3
Independent assays
12
Laboratories involved
Medutest, Kestrel, Janoshik, Nordanalyt
Provenance mix
Supplier-supplied ×12
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 12
Median purity 99.93% n=12
Spread (max − min) 0.26pp n=12
Standard deviation 0.075pp n=12
98.899.099.299.499.699.8100.0This lot (QYB-2503-Y6694)This lot (QYB-2503-Y6694): Q1 99.92, median 99.93, Q3 99.93, n=12outlier 99.67outlier 99.88outlier 99.90n=12All DihexaAll Dihexa: Q1 99.44, median 99.84, Q3 99.93, n=35n=35 Purity (% area)
Figure 1. This lot's independent purity results against the whole Dihexa record set in the index. The vertical line is the index acceptance specification for the neuroactive and cognitive peptides class, 98.5 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 12

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2025-018676QYB-2503-Y6694Medutest2025-Q399.937.81107.2Supplier-supplied1MARGINAL
AX-2025-018677QYB-2503-Y6694Kestrel2025-Q399.938.20Supplier-supplied1MARGINAL
AX-2025-018678QYB-2503-Y6694Janoshik2025-Q399.677.09Supplier-supplied1MARGINAL
AX-2025-018679QYB-2503-Y6694Janoshik2025-Q399.938.19107.5Supplier-supplied1MARGINAL
AX-2025-018680QYB-2503-Y6694Nordanalyt2025-Q399.907.77Supplier-supplied1MARGINAL
AX-2025-018681QYB-2503-Y6694Medutest2025-Q399.887.09100.0Supplier-supplied1MARGINAL
AX-2025-018682QYB-2503-Y6694Kestrel2025-Q399.937.88Supplier-supplied0PASS
AX-2025-018683QYB-2503-Y6694Medutest2025-Q399.937.57Supplier-supplied1MARGINAL
AX-2025-018684QYB-2503-Y6694Janoshik2025-Q399.937.9391.4Supplier-supplied0PASS
AX-2025-018685QYB-2503-Y6694Janoshik2025-Q399.937.03Supplier-supplied1MARGINAL
AX-2025-018686QYB-2503-Y6694Janoshik2025-Q399.937.89105.8Supplier-supplied0PASS
AX-2025-018687QYB-2503-Y6694Medutest2025-Q399.937.58Supplier-supplied1MARGINAL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Medutest499.93, 99.88, 99.93, 99.9399.9325min+0.0899.85
Kestrel299.93, 99.9399.9315min+0.2499.69
Janoshik599.67, 99.93, 99.93, 99.93, 99.9399.9330min+0.0099.93
Nordanalyt199.9099.9035min+0.0299.88

This lot contributes 6 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)99.9099.93divergence -0.03 pp vs batch median
Total impurities (% area)0.100.07
Largest single impurity (% area)0.050.04
Water (%)not stated7.81
Counter-ion (%)4.2N/A
Peptide content (%w/w)91.791.88
Endotoxin (EU/mg)not statednot determined
Method stated on certificateYEScolumn, gradient and wavelength given
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
des-hexanoyl (−98 Da)12 / 120.050.04–0.24
[D-Ile]-epimer8 / 120.020.01–0.04
free acid (+1 Da)6 / 120.030.03–0.05
hexanoyl bis-adduct (+98 Da)2 / 120.030.02–0.03
Section 7

What this rollup does not establish