AssayIndex

SWB-2405-L5945

NAD+ · 1000 mg declared · Shanghai Wibson Biotechnology Co., Ltd. · manufactured 10 May 2024

CHARACTERISED
Lot code
SWB-2405-L5945
Supplier
SWB — Shanghai Wibson Biotechnology Co., Ltd.
Compound
NAD+
Compound class
Non-peptide adjuncts
Declared label claim
1000mg
Manufacture date
10 May 2024
Index quarter
2024-Q3
Independent assays
8
Laboratories involved
Medutest, Nordanalyt, Janoshik
Provenance mix
Buyer-sourced ×1 · Supplier-supplied ×7
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 8
Median purity 98.97% n=8
Spread (max − min) 1.16pp n=8
Standard deviation 0.365pp n=8
97.397.898.398.799.299.7100.1This lot (SWB-2405-L5945)This lot (SWB-2405-L5945): Q1 98.79, median 98.97, Q3 99.18, n=8n=8All NAD+All NAD+: Q1 98.35, median 98.88, Q3 99.38, n=48n=48 Purity (% area)
Figure 1. This lot's independent purity results against the whole NAD+ record set in the index. The vertical line is the index acceptance specification for the non-peptide adjuncts class, 97.0 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 8

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2024-004873SWB-2405-L5945Medutest2024-Q398.879.49105.2Supplier-supplied1FAIL
AX-2024-004874SWB-2405-L5945Nordanalyt2024-Q398.849.6089.9Supplier-supplied1MARGINAL
AX-2024-004875SWB-2405-L5945Janoshik2024-Q399.199.10Supplier-supplied0PASS
AX-2024-004876SWB-2405-L5945Janoshik2024-Q399.189.29Supplier-supplied0PASS
AX-2024-004877SWB-2405-L5945Nordanalyt2024-Q398.529.87100.2Buyer-sourced0PASS
AX-2024-004878SWB-2405-L5945Janoshik2024-Q399.079.30100.0Supplier-supplied0PASS
AX-2024-004879SWB-2405-L5945Medutest2024-Q399.689.3988.8Supplier-supplied2FAIL
AX-2024-004880SWB-2405-L5945Janoshik2024-Q398.659.0791.4Supplier-supplied0PASS
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Medutest298.87, 99.6899.2825min+0.0899.20
Nordanalyt298.84, 98.5298.6835min+0.0298.66
Janoshik499.19, 99.18, 99.07, 98.6599.1330min+0.0099.13

This lot contributes 3 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)99.3198.87divergence +0.34 pp vs batch median
Total impurities (% area)0.691.13
Largest single impurity (% area)not stated0.64
Water (%)7.89.49
Counter-ion (%)not statedN/A
Peptide content (%w/w)not stated89.58
Endotoxin (EU/mg)0.34not determined
Method stated on certificateYEScolumn, gradient and wavelength given
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
ADP-ribose (−121 Da)8 / 80.360.15–0.83
nicotinamide mononucleotide (NMN, −331 Da)8 / 80.380.10–0.64
NADH (reduced, +2 Da)8 / 80.100.04–0.16
nicotinamide (−541 Da)8 / 80.060.03–0.10
α-NAD anomer7 / 80.060.03–0.09
Section 7

What this rollup does not establish