AssayIndex
Metabolic and mitochondrial peptides

Adipotide

FTPP · prohibitin-targeting peptidomimetic · CKGGRAKDC-GG-D(KLAKLAK)2 · C190H332N60O43 · monoisotopic 4095.6238 Da. The index holds 16 assay reports on this compound across 5 batches from 4 suppliers.

16 reports5 batchesmedian 98.59 %index spec 96.0 %
Section 1

Analytical fingerprint

Hand-authored chemistry. These properties describe the substance and do not change when a record is added.

Adipotide is a chimeric peptidomimetic with a cyclised targeting motif and a highly cationic pro-apoptotic domain. Long, repetitive and strongly basic — the three properties that make a synthesis hard — and it has the lowest purity distribution of any peptide in the index (median 95.9 %). The repeat sequence means deletion impurities differ by whole heptad units and are chromatographically distinct, which at least makes them countable. Thin coverage.

Molecular formula
C190H332N60O43
Monoisotopic mass
4095.6238Da
Average mass
4098.00Da
Residues
30
Nominal retention (RG-2, 30 min)
12.74min
Retention window
0.35min
Counter-ion as usually shipped
TFA
Typical label claims
2 mg · 5 mg · 10 mg
Analytical difficulty (index scale)
1.35 — moderate
Purity is a defined quantity
YES
Section 2

Representative chromatogram

Drawn from this page's own medians. Not a scan, not an illustration, and not any single report.

02090418062708359 Adipotide12.74 min · 98.59 % 13.1811.12 same trace · ×100 vertical expansion, baseline-corrected · main peak off-scale reporting threshold 0.05 % area 05101520253035 Retention time (min) Response (mAU)
Figure 1. A representative Adipotide trace on the index reference method RG-2, constructed from this page's own numbers: the main peak carries the index median purity of 98.59 % area at the nominal retention time of 12.74 min, and each impurity peak carries the median area the index has observed for that named species at its characteristic retention offset. It is not a scan of any single report — every individual record's own chromatogram is on its own page. The lower panel is the same trace at a stated vertical expansion, baseline-corrected, so the impurities are visible; the main peak runs off-scale there by design. Baseline noise is seeded from the compound slug.
Section 3

What the index has observed

Arithmetic over the 16 records the index holds. Aggregates on this page are computed over the records the index holds, which are not a random sample of the material on the market. Lots that get tested are lots someone chose to test. Read every figure here as a description of this dataset rather than as an estimate of a population.

Median purity 98.59% n=16
Interquartile range 0.69pp n=16
Minimum 97.04% n=16
Maximum 99.53% n=16
Pass rate vs spec 100.0% n=16
Median recovery vs claim 96.9% n=11
Median water 3.23% n=16
Median |mass error| 3.0ppm n=12
02492.093.094.095.096.097.098.099.0100.092.00–92.25 %: n=092.25–92.50 %: n=092.50–92.75 %: n=092.75–93.00 %: n=093.00–93.25 %: n=093.25–93.50 %: n=093.50–93.75 %: n=093.75–94.00 %: n=094.00–94.25 %: n=094.25–94.50 %: n=094.50–94.75 %: n=094.75–95.00 %: n=095.00–95.25 %: n=095.25–95.50 %: n=095.50–95.75 %: n=095.75–96.00 %: n=096.00–96.25 %: n=096.25–96.50 %: n=096.50–96.75 %: n=096.75–97.00 %: n=097.00–97.25 %: n=297.25–97.50 %: n=097.50–97.75 %: n=097.75–98.00 %: n=198.00–98.25 %: n=198.25–98.50 %: n=298.50–98.75 %: n=498.75–99.00 %: n=399.00–99.25 %: n=299.25–99.50 %: n=099.50–99.75 %: n=199.75–100.00 %: n=0median 98.59 Purity (% area) Reports
Figure 2. Purity distribution across all 16 Adipotide records. Dashed line is this compound's median (98.59 %); the solid vertical is the index acceptance specification for the metabolic and mitochondrial peptides class (96.0 %). Domain is fixed at 92–100 % on every purity histogram on this site so that compounds can be compared by eye — a wide distribution here is a hard compound, a narrow one is an easy one, and neither is a statement about the suppliers.
Section 4

By supplier

Suppliers with fewer than two purity records on this compound are omitted from the figure rather than drawn as a line. The full table, including the thin cells, is on the by-supplier page.

96.897.397.898.398.899.299.7WWBWWB: Q1 98.60, median 98.83, Q3 99.17, n=9n=9MKMMKM: Q1 97.48, median 97.92, Q3 98.25, n=3n=3TFCTFC: Q1 98.44, median 98.59, Q3 98.75, n=2n=2CPCCPC: Q1 97.39, median 97.61, Q3 97.82, n=2n=2 Purity (% area)
Figure 3. Adipotide purity by supplier, ordered by coverage. The vertical line is the index acceptance specification. Boxes that overlap are suppliers this dataset cannot separate, and most of them overlap.

Full per-supplier table with n= caveats →

Section 5

Characteristic impurities and degradants

The left three columns are authored chemistry — what this molecule characteristically carries and where it elutes. The right three are what the index has actually reported.

Named speciesΔRT (min, RG-2)Δ mass (Da)Seen inMedian % areaMax % area
open-chain (reduced disulfide, +2 Da)-1.05+2.016100%0.191.97
truncated KLAKLAK repeat (−781 Da)-1.62-781.512100%0.321.97
disulfide-scrambled isomer+0.44mass-identical100%0.391.20
trifluoroacetyl adduct (+96 Da)+0.82+95.982100%0.130.75

Degradation pathways

  • disulfide reduction
  • aggregation of the cationic KLAKLAK domain

Full impurity profile, with what each named species implies about the synthesis →

Section 7

Quarterly coverage

QuarterReportsMedian purityRange
2024-Q10n<3—
2024-Q20n<3—
2024-Q30n<3—
2024-Q40n<3—
2025-Q10n<3—
2025-Q2498.1797.17–98.90
2025-Q30n<3—
2025-Q40n<3—
2026-Q11n<3—
2026-Q2998.8398.32–99.53
2026-Q32n<397.04–97.92

Quarter-by-quarter detail →

Section 8

Most recent records

The 25 most recent Adipotide records of 16.
ReportSupplierLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-042943MKMMKM-2606-K4013Janoshik2026-Q397.926.31—Supplier-supplied1MARGINAL
AX-2026-042942MKMMKM-2606-K4013VendorInvestigate2026-Q397.045.5694.6Buyer-sourced1FAIL
AX-2026-041394WWBWWB-2512-R4093Janoshik2026-Q299.533.42—Supplier-supplied2MARGINAL
AX-2026-041396WWBWWB-2512-R4093Janoshik2026-Q298.963.0094.7Supplier-supplied2MARGINAL
AX-2026-041391WWBWWB-2512-R4093Kestrel2026-Q298.833.0798.2Supplier-supplied4FAIL
AX-2026-041395WWBWWB-2512-R4093Medutest2026-Q299.203.03—Supplier-supplied2MARGINAL
AX-2026-041392WWBWWB-2512-R4093Janoshik2026-Q298.742.5489.2Laboratory-retained2MARGINAL
AX-2026-041399WWBWWB-2512-R4093Janoshik2026-Q299.173.04—Supplier-supplied2MARGINAL
AX-2026-041393WWBWWB-2512-R4093VendorInvestigate2026-Q298.323.3598.7Buyer-sourced1MARGINAL
AX-2026-041398WWBWWB-2512-R4093Janoshik2026-Q298.572.94105.0Laboratory-retained1MARGINAL
AX-2026-041397WWBWWB-2512-R4093Janoshik2026-Q298.603.4090.2Laboratory-retained1MARGINAL
AX-2026-042908MKMMKM-2511-F2657Medutest2026-Q198.595.6196.9Supplier-supplied0PASS
AX-2025-019219TFCTFC-2411-R5803Medutest2025-Q298.903.1099.4Supplier-supplied1FAIL
AX-2025-020846CPCCPC-2502-C1391Nordanalyt2025-Q297.175.1590.6Buyer-sourced1MARGINAL
AX-2025-020847CPCCPC-2502-C1391Janoshik2025-Q298.045.51106.3Supplier-supplied2MARGINAL
AX-2025-019218TFCTFC-2411-R5803Janoshik2025-Q298.292.85—Supplier-supplied0PASS