Cross-section

Adipotide by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for Adipotide, with a class minimum gradient of 15 min, the method is a live explanation.

16 recordsmedian 98.59 %spec 96.0 %

Laboratory	Reports	Gradient	MS resolution	Median purity %	Published bias (pp)	Bias-adjusted	Method suitability
Janoshik	9	30min	High	98.60	+0.00	98.60	ADEQUATE
Medutest	3 n=3	25min	Unit	98.90	+0.08	98.82	ADEQUATE
VendorInvestigate	2 n=2	32min	High	97.04, 98.32	-0.11	—	ADEQUATE
Nordanalyt	1 n=1	35min	High	97.17	+0.02	—	ADEQUATE
Kestrel	1 n=1	15min	Unit	98.83	+0.24	—	ADEQUATE
PeptideMeter	0	28min	High	—	-0.05	—	ADEQUATE

Figure. Adipotide purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.