AOD-9604 impurity profile
Every named species the index has reported alongside AOD-9604, how often, at what level, and what its presence implies about the synthesis or the handling. Reporting threshold is 0.05 % area; anything below it is invisible to this page and is silently added to the main peak.
Median total impurities
0.75%
n=89
Median largest single
0.35%
n=89
Worst single observed
1.69%
n=89
Named species observed
4 / 4
n=4
| Named species | ΔRT (min) | Δ mass (Da) | Seen in | Median % area | Max % area |
|---|---|---|---|---|---|
| Met sulfoxide (+16 Da) | -0.44 | +15.995 | 96% | 0.12 | 0.75 |
| open-chain (reduced disulfide, +2 Da) | -0.61 | +2.016 | 93% | 0.11 | 1.69 |
| AOD dimer | +2.10 | +1813.852 | 89% | 0.12 | 0.86 |
| des-Tyr AOD (−163 Da) | -0.84 | -163.063 | 85% | 0.15 | 1.32 |
Met sulfoxide (+16 Da)
- Retention offset from the main peak
- -0.44 min on RG-2
- Mass difference
- +15.995 Da
- Reported in
- 85 of 89 records (96 %)
- Level when reported
- median 0.12 %, max 0.75 %
- Resolution requirement
- Baseline-resolved on the reference method.
open-chain (reduced disulfide, +2 Da)
- Retention offset from the main peak
- -0.61 min on RG-2
- Mass difference
- +2.016 Da
- Reported in
- 83 of 89 records (93 %)
- Level when reported
- median 0.11 %, max 1.69 %
- Resolution requirement
- Baseline-resolved on the reference method.
AOD dimer
- Retention offset from the main peak
- +2.10 min on RG-2
- Mass difference
- +1813.852 Da
- Reported in
- 79 of 89 records (89 %)
- Level when reported
- median 0.12 %, max 0.86 %
- Resolution requirement
- Baseline-resolved on the reference method.
des-Tyr AOD (−163 Da)
- Retention offset from the main peak
- -0.84 min on RG-2
- Mass difference
- -163.063 Da
- Reported in
- 76 of 89 records (85 %)
- Level when reported
- median 0.15 %, max 1.32 %
- Resolution requirement
- Baseline-resolved on the reference method.
Degradation pathways
Degradants are a handling finding rather than a synthesis finding. A lot that shipped clean and arrived oxidised tells you about the courier, not the chemist.
- disulfide reduction
- Met oxidation