AssayIndex
Metabolic and mitochondrial peptides

AOD-9604

hGH fragment 176-191 (Tyr-) · AOD9604 · C78H123N23O23S2 · monoisotopic 1815.8672 Da. The index holds 89 assay reports on this compound across 15 batches from 7 suppliers.

89 reports15 batchesmedian 99.25 %index spec 98.0 %
Section 1

Analytical fingerprint

Hand-authored chemistry. These properties describe the substance and do not change when a record is added.

AOD-9604 is a 16-residue disulfide-containing fragment and the most frequently mislabelled compound in the index: "HGH Frag 176-191" is sold as both the native fragment and the N-terminally tyrosinated AOD-9604, a 163 Da difference that is unmissable by MS and invisible by HPLC alone. Roughly one in nine submissions labelled AOD-9604 masses as the untyrosinated fragment. The index records both and cross-links them; it does not treat either as an adulteration, only as a labelling error.

Molecular formula
C78H123N23O23S2
Monoisotopic mass
1815.8672Da
Average mass
1817.12Da
Residues
16
Nominal retention (RG-2, 30 min)
11.28min
Retention window
0.30min
Counter-ion as usually shipped
acetate
Typical label claims
2 mg · 5 mg · 10 mg
Analytical difficulty (index scale)
0.95 — straightforward
Purity is a defined quantity
YES
Section 2

Representative chromatogram

Drawn from this page's own medians. Not a scan, not an illustration, and not any single report.

02376475271289504 AOD-960411.28 min · 99.25 % 10.4413.38 same trace · ×200 vertical expansion, baseline-corrected · main peak off-scale reporting threshold 0.05 % area 05101520253035 Retention time (min) Response (mAU)
Figure 1. A representative AOD-9604 trace on the index reference method RG-2, constructed from this page's own numbers: the main peak carries the index median purity of 99.25 % area at the nominal retention time of 11.28 min, and each impurity peak carries the median area the index has observed for that named species at its characteristic retention offset. It is not a scan of any single report — every individual record's own chromatogram is on its own page. The lower panel is the same trace at a stated vertical expansion, baseline-corrected, so the impurities are visible; the main peak runs off-scale there by design. Baseline noise is seeded from the compound slug.
Section 3

What the index has observed

Arithmetic over the 89 records the index holds. Aggregates on this page are computed over the records the index holds, which are not a random sample of the material on the market. Lots that get tested are lots someone chose to test. Read every figure here as a description of this dataset rather than as an estimate of a population.

Median purity 99.25% n=89
Interquartile range 0.93pp n=89
Minimum 97.11% n=89
Maximum 99.93% n=89
Pass rate vs spec 93.3% n=89
Median recovery vs claim 97.9% n=51
Median water 3.82% n=89
Median |mass error| 2.2ppm n=75
06121892.093.094.095.096.097.098.099.0100.092.00–92.25 %: n=092.25–92.50 %: n=092.50–92.75 %: n=092.75–93.00 %: n=093.00–93.25 %: n=093.25–93.50 %: n=093.50–93.75 %: n=093.75–94.00 %: n=094.00–94.25 %: n=094.25–94.50 %: n=094.50–94.75 %: n=094.75–95.00 %: n=095.00–95.25 %: n=095.25–95.50 %: n=095.50–95.75 %: n=095.75–96.00 %: n=096.00–96.25 %: n=096.25–96.50 %: n=096.50–96.75 %: n=096.75–97.00 %: n=097.00–97.25 %: n=197.25–97.50 %: n=097.50–97.75 %: n=297.75–98.00 %: n=398.00–98.25 %: n=598.25–98.50 %: n=298.50–98.75 %: n=598.75–99.00 %: n=1299.00–99.25 %: n=1499.25–99.50 %: n=1299.50–99.75 %: n=1299.75–100.00 %: n=21median 99.25 Purity (% area) Reports
Figure 2. Purity distribution across all 89 AOD-9604 records. Dashed line is this compound's median (99.25 %); the solid vertical is the index acceptance specification for the metabolic and mitochondrial peptides class (98.0 %). Domain is fixed at 92–100 % on every purity histogram on this site so that compounds can be compared by eye — a wide distribution here is a hard compound, a narrow one is an easy one, and neither is a statement about the suppliers.
Section 4

By supplier

Suppliers with fewer than two purity records on this compound are omitted from the figure rather than drawn as a line. The full table, including the thin cells, is on the by-supplier page.

96.997.498.098.599.199.6100.2QSCQSC: Q1 99.37, median 99.77, Q3 99.89, n=18n=18HJHJ: Q1 98.37, median 98.78, Q3 98.94, n=15n=15TFCTFC: Q1 99.55, median 99.73, Q3 99.93, n=15n=15QYBQYB: Q1 99.46, median 99.65, Q3 99.93, n=13outlier 98.73n=13BCHBCH: Q1 97.95, median 98.30, Q3 98.72, n=11n=11SWBSWB: Q1 98.96, median 99.14, Q3 99.19, n=9outlier 99.60n=9MKMMKM: Q1 98.34, median 98.95, Q3 99.11, n=8n=8 Purity (% area)
Figure 3. AOD-9604 purity by supplier, ordered by coverage. The vertical line is the index acceptance specification. Boxes that overlap are suppliers this dataset cannot separate, and most of them overlap.

Full per-supplier table with n= caveats →

Section 5

Characteristic impurities and degradants

The left three columns are authored chemistry — what this molecule characteristically carries and where it elutes. The right three are what the index has actually reported.

Named speciesΔRT (min, RG-2)Δ mass (Da)Seen inMedian % areaMax % area
Met sulfoxide (+16 Da)-0.44+15.99596%0.120.75
open-chain (reduced disulfide, +2 Da)-0.61+2.01693%0.111.69
AOD dimer+2.10+1813.85289%0.120.86
des-Tyr AOD (−163 Da)-0.84-163.06385%0.151.32

Degradation pathways

  • disulfide reduction
  • Met oxidation

Full impurity profile, with what each named species implies about the synthesis →

Section 7

Quarterly coverage

QuarterReportsMedian purityRange
2024-Q10n<3—
2024-Q2699.8499.46–99.93
2024-Q3999.9098.83–99.93
2024-Q40n<3—
2025-Q11098.8997.85–99.60
2025-Q21199.0697.52–99.46
2025-Q31799.2398.30–99.86
2025-Q42199.5497.11–99.93
2026-Q1899.6498.73–99.93
2026-Q2798.8598.14–99.02
2026-Q30n<3—

Quarter-by-quarter detail →

Section 8

Most recent records

The 25 most recent AOD-9604 records of 89.
ReportSupplierLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-042300HJHJ-2601-N2483Janoshik2026-Q298.775.32—Buyer-sourced1MARGINAL
AX-2026-042297HJHJ-2601-N2483Medutest2026-Q299.004.7299.5Supplier-supplied1MARGINAL
AX-2026-042299HJHJ-2601-N2483VendorInvestigate2026-Q298.145.21103.7Buyer-sourced1MARGINAL
AX-2026-042296HJHJ-2601-N2483Janoshik2026-Q298.855.7697.1Supplier-supplied1MARGINAL
AX-2026-042301HJHJ-2601-N2483VendorInvestigate2026-Q298.605.3697.9Buyer-sourced1MARGINAL
AX-2026-042298HJHJ-2601-N2483Janoshik2026-Q299.025.1496.5Supplier-supplied1MARGINAL
AX-2026-042295HJHJ-2601-N2483Medutest2026-Q298.885.8093.8Supplier-supplied1MARGINAL
AX-2026-041474QYBQYB-2508-E6017Janoshik2026-Q199.623.75—Supplier-supplied0PASS
AX-2026-041476QYBQYB-2508-E6017Janoshik2026-Q199.653.82104.9Supplier-supplied0PASS
AX-2026-041475QYBQYB-2508-E6017Kestrel2026-Q199.933.65—Supplier-supplied0PASS
AX-2026-041477QYBQYB-2508-E6017Janoshik2026-Q199.753.85102.0Supplier-supplied0PASS
AX-2026-041473QYBQYB-2508-E6017Janoshik2026-Q199.324.06—Supplier-supplied0PASS
AX-2026-041479QYBQYB-2508-E6017Medutest2026-Q198.733.90107.4Supplier-supplied0PASS
AX-2026-041478QYBQYB-2508-E6017Janoshik2026-Q199.773.59—Supplier-supplied0PASS
AX-2026-041472QYBQYB-2508-E6017PeptideMeter2026-Q199.303.4691.9Supplier-supplied0PASS
AX-2026-042001TFCTFC-2511-L5476Janoshik2025-Q499.933.3699.3Supplier-supplied0PASS
AX-2026-042002TFCTFC-2511-L5476Kestrel2025-Q499.933.49104.4Supplier-supplied0PASS
AX-2025-019176TFCTFC-2511-L5476PeptideMeter2025-Q499.183.10—Supplier-supplied0PASS
AX-2025-021231BCHBCH-2509-K6299VendorInvestigate2025-Q497.114.8891.7Buyer-sourced1FAIL
AX-2025-021233BCHBCH-2509-K6299VendorInvestigate2025-Q497.884.41—Buyer-sourced1FAIL
AX-2025-019183TFCTFC-2511-L5476Kestrel2025-Q499.543.68—Supplier-supplied0PASS
AX-2025-021230BCHBCH-2509-K6299Janoshik2025-Q498.035.1689.4Laboratory-retained2MARGINAL
AX-2025-019178TFCTFC-2511-L5476Medutest2025-Q499.933.02105.3Supplier-supplied0PASS
AX-2025-021235BCHBCH-2509-K6299Medutest2025-Q498.184.48—Buyer-sourced1MARGINAL
AX-2025-021236BCHBCH-2509-K6299Janoshik2025-Q498.684.31106.3Supplier-supplied1MARGINAL