Cross-section

Gonadorelin by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for Gonadorelin, with a class minimum gradient of 15 min, the method is a live explanation.

49 recordsmedian 99.28 %spec 98.5 %

Laboratory	Reports	Gradient	MS resolution	Median purity %	Published bias (pp)	Bias-adjusted	Method suitability
Janoshik	26	30min	High	99.10	+0.00	99.10	ADEQUATE
PeptideMeter	8	28min	High	99.47	-0.05	99.52	ADEQUATE
Medutest	6 n=6	25min	Unit	99.31	+0.08	99.23	ADEQUATE
VendorInvestigate	4 n=4	32min	High	98.83	-0.11	98.94	ADEQUATE
Nordanalyt	3 n=3	35min	High	99.62	+0.02	99.60	ADEQUATE
Kestrel	2 n=2	15min	Unit	99.76, 99.52	+0.24	—	ADEQUATE

Figure. Gonadorelin purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.