AssayIndex
Melanocortin-receptor peptides

Kisspeptin-10

KP-10 · metastin (45-54) · C63H83N17O14 · monoisotopic 1301.6300 Da. The index holds 70 assay reports on this compound across 13 batches from 9 suppliers.

70 reports13 batchesmedian 99.27 %index spec 98.5 %
Section 1

Analytical fingerprint

Hand-authored chemistry. These properties describe the substance and do not change when a record is added.

Kisspeptin-10's C-terminal amide is essential, and the +1 Da free acid is both the commonest impurity and a functional one. The index reports it separately. Otherwise a routine decapeptide assay.

Molecular formula
C63H83N17O14
Monoisotopic mass
1301.6300Da
Average mass
1302.46Da
Residues
10
Nominal retention (RG-2, 30 min)
9.14min
Retention window
0.25min
Counter-ion as usually shipped
acetate
Typical label claims
5 mg · 10 mg
Analytical difficulty (index scale)
0.90 — straightforward
Purity is a defined quantity
YES
Section 2

Representative chromatogram

Drawn from this page's own medians. Not a scan, not an illustration, and not any single report.

029335866879911731 Kisspeptin-109.14 min · 99.27 % 8.80 same trace · ×200 vertical expansion, baseline-corrected · main peak off-scale reporting threshold 0.05 % area 05101520253035 Retention time (min) Response (mAU)
Figure 1. A representative Kisspeptin-10 trace on the index reference method RG-2, constructed from this page's own numbers: the main peak carries the index median purity of 99.27 % area at the nominal retention time of 9.14 min, and each impurity peak carries the median area the index has observed for that named species at its characteristic retention offset. It is not a scan of any single report — every individual record's own chromatogram is on its own page. The lower panel is the same trace at a stated vertical expansion, baseline-corrected, so the impurities are visible; the main peak runs off-scale there by design. Baseline noise is seeded from the compound slug.
Section 3

What the index has observed

Arithmetic over the 70 records the index holds. Aggregates on this page are computed over the records the index holds, which are not a random sample of the material on the market. Lots that get tested are lots someone chose to test. Read every figure here as a description of this dataset rather than as an estimate of a population.

Median purity 99.27% n=70
Interquartile range 1.28pp n=70
Minimum 97.89% n=70
Maximum 99.93% n=70
Pass rate vs spec 74.3% n=70
Median recovery vs claim 97.0% n=46
Median water 4.67% n=70
Median |mass error| 2.8ppm n=64
06121892.093.094.095.096.097.098.099.0100.092.00–92.25 %: n=092.25–92.50 %: n=092.50–92.75 %: n=092.75–93.00 %: n=093.00–93.25 %: n=093.25–93.50 %: n=093.50–93.75 %: n=093.75–94.00 %: n=094.00–94.25 %: n=094.25–94.50 %: n=094.50–94.75 %: n=094.75–95.00 %: n=095.00–95.25 %: n=095.25–95.50 %: n=095.50–95.75 %: n=095.75–96.00 %: n=096.00–96.25 %: n=096.25–96.50 %: n=096.50–96.75 %: n=096.75–97.00 %: n=097.00–97.25 %: n=097.25–97.50 %: n=097.50–97.75 %: n=097.75–98.00 %: n=498.00–98.25 %: n=798.25–98.50 %: n=798.50–98.75 %: n=698.75–99.00 %: n=599.00–99.25 %: n=499.25–99.50 %: n=1199.50–99.75 %: n=799.75–100.00 %: n=19median 99.27 Purity (% area) Reports
Figure 2. Purity distribution across all 70 Kisspeptin-10 records. Dashed line is this compound's median (99.27 %); the solid vertical is the index acceptance specification for the melanocortin-receptor peptides class (98.5 %). Domain is fixed at 92–100 % on every purity histogram on this site so that compounds can be compared by eye — a wide distribution here is a hard compound, a narrow one is an easy one, and neither is a statement about the suppliers.
Section 4

By supplier

Suppliers with fewer than two purity records on this compound are omitted from the figure rather than drawn as a line. The full table, including the thin cells, is on the by-supplier page.

97.798.198.598.999.399.7100.1WWBWWB: Q1 99.50, median 99.86, Q3 99.93, n=13n=13SWBSWB: Q1 98.38, median 98.56, Q3 98.94, n=10n=10QSCQSC: Q1 99.54, median 99.66, Q3 99.84, n=10n=10QYBQYB: Q1 99.71, median 99.93, Q3 99.93, n=9n=9CPCCPC: Q1 97.94, median 98.21, Q3 98.34, n=9n=9GL BiochemGL Biochem: Q1 98.23, median 98.31, Q3 98.57, n=7outlier 99.32n=7ERPERP: Q1 98.87, median 98.99, Q3 99.21, n=6outlier 98.19n=6TFCTFC: Q1 98.82, median 99.27, Q3 99.28, n=5n=5 Purity (% area)
Figure 3. Kisspeptin-10 purity by supplier, ordered by coverage. The vertical line is the index acceptance specification. Boxes that overlap are suppliers this dataset cannot separate, and most of them overlap.

Full per-supplier table with n= caveats →

Section 5

Characteristic impurities and degradants

The left three columns are authored chemistry — what this molecule characteristically carries and where it elutes. The right three are what the index has actually reported.

Named speciesΔRT (min, RG-2)Δ mass (Da)Seen inMedian % areaMax % area
des-Tyr (−163 Da)-0.56-163.06393%0.160.69
C-terminal free acid (+1 Da)+0.18+0.98493%0.130.46
oxidised Trp (+16 Da)-0.34+15.99586%0.241.29
[D-Trp]-epimer-0.12mass-identical84%0.181.15

Degradation pathways

  • Trp oxidation
  • C-terminal amide hydrolysis — the amide is required for activity

Full impurity profile, with what each named species implies about the synthesis →

Section 7

Quarterly coverage

QuarterReportsMedian purityRange
2024-Q11n<3—
2024-Q21799.5598.19–99.93
2024-Q32n<399.27–99.46
2024-Q4998.2197.89–98.90
2025-Q1999.5799.09–99.93
2025-Q21n<3—
2025-Q30n<3—
2025-Q41n<3—
2026-Q10n<3—
2026-Q21399.7198.39–99.93
2026-Q31798.4797.97–99.55

Quarter-by-quarter detail →

Section 8

Most recent records

The 25 most recent Kisspeptin-10 records of 70.
ReportSupplierLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-042461SWBSWB-2603-D6238Janoshik2026-Q398.354.6596.5Supplier-supplied3FAIL
AX-2026-043176GL BiochemGLBI-2608-N8085Medutest2026-Q398.223.3092.5Buyer-sourced2FAIL
AX-2026-043180GL BiochemGLBI-2608-N8085Janoshik2026-Q398.693.37103.8Supplier-supplied2MARGINAL
AX-2026-042460SWBSWB-2603-D6238Kestrel2026-Q399.554.2190.8Supplier-supplied3MARGINAL
AX-2026-042458SWBSWB-2603-D6238Kestrel2026-Q398.514.71102.4Supplier-supplied3MARGINAL
AX-2026-043178GL BiochemGLBI-2608-N8085Janoshik2026-Q398.244.4496.0Supplier-supplied2FAIL
AX-2026-042463SWBSWB-2603-D6238Nordanalyt2026-Q398.354.9398.6Supplier-supplied3FAIL
AX-2026-042465SWBSWB-2603-D6238Kestrel2026-Q399.034.8396.4Supplier-supplied3MARGINAL
AX-2026-042462SWBSWB-2603-D6238Janoshik2026-Q398.614.7396.5Supplier-supplied3MARGINAL
AX-2026-043177GL BiochemGLBI-2608-N8085Janoshik2026-Q398.313.87106.5Buyer-sourced2FAIL
AX-2026-043174GL BiochemGLBI-2608-N8085Medutest2026-Q398.184.09—Laboratory-retained2FAIL
AX-2026-043179GL BiochemGLBI-2608-N8085Janoshik2026-Q398.453.90—Laboratory-retained2FAIL
AX-2026-043175GL BiochemGLBI-2608-N8085Kestrel2026-Q399.323.5199.8Supplier-supplied2MARGINAL
AX-2026-042464SWBSWB-2603-D6238Medutest2026-Q399.385.0192.5Supplier-supplied4FAIL
AX-2026-042466SWBSWB-2603-D6238Janoshik2026-Q398.474.6894.5Supplier-supplied3FAIL
AX-2026-042467SWBSWB-2603-D6238Janoshik2026-Q397.975.39—Laboratory-retained4FAIL
AX-2026-042459SWBSWB-2603-D6238PeptideMeter2026-Q398.664.6288.5Supplier-supplied4MARGINAL
AX-2026-041500QYBQYB-2512-X5662Janoshik2026-Q299.934.3488.6Supplier-supplied1MARGINAL
AX-2026-041503QYBQYB-2512-X5662PeptideMeter2026-Q299.403.81—Supplier-supplied1MARGINAL
AX-2026-041502QYBQYB-2512-X5662Janoshik2026-Q299.934.03—Supplier-supplied1MARGINAL
AX-2026-041497QYBQYB-2512-X5662Janoshik2026-Q299.454.4588.6Supplier-supplied2MARGINAL
AX-2026-041499QYBQYB-2512-X5662Nordanalyt2026-Q299.934.38103.6Supplier-supplied0PASS
AX-2026-043234SGNSGN-2601-A1088PeptideMeter2026-Q298.394.36—Supplier-supplied2FAIL
AX-2026-041501QYBQYB-2512-X5662Nordanalyt2026-Q299.933.58107.3Supplier-supplied2MARGINAL
AX-2026-041504QYBQYB-2512-X5662Janoshik2026-Q299.934.0391.8Supplier-supplied1MARGINAL