AssayIndex
Cross-section

Semaglutide by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for Semaglutide, with a class minimum gradient of 25 min, the method is a live explanation.

926 recordsmedian 98.87 %spec 97.0 %
LaboratoryReportsGradientMS resolutionMedian purity %Published bias (pp)Bias-adjustedMethod suitability
Janoshik40430minHigh98.87+0.0098.87ADEQUATE
Medutest14525minUnit99.05+0.0898.97ADEQUATE
PeptideMeter14128minHigh98.85-0.0598.90ADEQUATE
VendorInvestigate10232minHigh98.37-0.1198.48ADEQUATE
Nordanalyt7335minHigh98.96+0.0298.94ADEQUATE
Kestrel6115minUnit99.41+0.2499.17BELOW CLASS MINIMUM
96.196.897.598.298.899.5100.2JanoshikJanoshik: Q1 98.28, median 98.87, Q3 99.32, n=404outlier 96.37n=404PeptideMeterPeptideMeter: Q1 98.31, median 98.85, Q3 99.29, n=141outlier 96.77n=141MedutestMedutest: Q1 98.27, median 99.05, Q3 99.49, n=145n=145VendorInvestigateVendorInvestigate: Q1 97.88, median 98.37, Q3 98.87, n=102n=102NordanalytNordanalyt: Q1 98.32, median 98.96, Q3 99.21, n=73outlier 96.86n=73KestrelKestrel: Q1 98.97, median 99.41, Q3 99.93, n=61n=61 Purity (% area)
Figure. Semaglutide purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.