Solid-phase peptide synthesis (SPPS)
Stepwise chain assembly on an insoluble support, with excess reagent driving each coupling. The origin of almost every peptide in this index.
Related terms
- Coupling efficiency
- The fraction of resin-bound chains that react at each synthesis step. At 99.5 % per step, a 40-mer is 82 % full-length before purification.
- Fmoc
- Fluorenylmethyloxycarbonyl, the standard temporary amine protecting group in solid-phase synthesis. Residual Fmoc appears at +222.068 Da.
see also Deletion sequence
Where this term appears
The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.
- Assay report records — the term appears in result tables, peak tables and provenance blocks
- Method references — where the measurement behind the term is defined
- All 21 glossary terms beginning with S