Macrolactamisation
The cyclisation step forming a lactam bridge. Incomplete cyclisation leaves the linear precursor at +18.011 Da — the commonest process failure in the melanocortin class.
Related terms
- Lactam bridge
- A cyclisation through an amide bond between a side-chain carboxyl and a side-chain amine. Melanotan II and bremelanotide are lactam-cyclised.
see also Macrolactamisation
Where this term appears
The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.
- Assay report records — the term appears in result tables, peak tables and provenance blocks
- Method references — where the measurement behind the term is defined
- All 16 glossary terms beginning with M