AssayIndex

QSC-2412-D8489

BPC-157 · 5 mg declared · Qingdao Sigma Chemical Co., Ltd. · manufactured 25 Dec 2024

CHARACTERISED
Lot code
QSC-2412-D8489
Supplier
QSC — Qingdao Sigma Chemical Co., Ltd.
Compound
BPC-157
Compound class
Tissue-repair and immunomodulatory peptides
Declared label claim
5mg
Manufacture date
25 Dec 2024
Index quarter
2025-Q1
Independent assays
16
Laboratories involved
Janoshik, Medutest, PeptideMeter, Nordanalyt
Provenance mix
Buyer-sourced ×15 · Laboratory-retained ×1
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 16
Median purity 99.60% n=16
Spread (max − min) 0.64pp n=16
Standard deviation 0.198pp n=16
97.097.598.098.699.199.6100.1This lot (QSC-2412-D8489)This lot (QSC-2412-D8489): Q1 99.48, median 99.60, Q3 99.81, n=16n=16All BPC-157All BPC-157: Q1 98.69, median 99.24, Q3 99.71, n=638n=638 Purity (% area)
Figure 1. This lot's independent purity results against the whole BPC-157 record set in the index. The vertical line is the index acceptance specification for the tissue-repair and immunomodulatory peptides class, 98.0 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 16

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2025-018806QSC-2412-D8489Janoshik2025-Q199.575.6899.3Buyer-sourced1MARGINAL
AX-2025-018807QSC-2412-D8489Janoshik2025-Q199.296.60Buyer-sourced1MARGINAL
AX-2025-018808QSC-2412-D8489Medutest2025-Q199.935.8099.9Buyer-sourced1MARGINAL
AX-2025-018809QSC-2412-D8489Janoshik2025-Q199.605.88Buyer-sourced1MARGINAL
AX-2025-018810QSC-2412-D8489Janoshik2025-Q199.816.05Buyer-sourced1MARGINAL
AX-2025-018811QSC-2412-D8489PeptideMeter2025-Q199.485.68106.4Laboratory-retained2FAIL
AX-2025-018812QSC-2412-D8489PeptideMeter2025-Q199.606.0297.4Buyer-sourced1MARGINAL
AX-2025-018813QSC-2412-D8489PeptideMeter2025-Q199.936.4788.9Buyer-sourced2MARGINAL
AX-2025-018814QSC-2412-D8489Janoshik2025-Q199.476.2092.7Buyer-sourced1MARGINAL
AX-2025-018815QSC-2412-D8489Medutest2025-Q199.685.35Buyer-sourced1MARGINAL
AX-2025-018816QSC-2412-D8489Nordanalyt2025-Q199.626.13Buyer-sourced1MARGINAL
AX-2025-018817QSC-2412-D8489Janoshik2025-Q199.816.19100.3Buyer-sourced1MARGINAL
AX-2025-018818QSC-2412-D8489Janoshik2025-Q199.436.0996.5Buyer-sourced1MARGINAL
AX-2025-018819QSC-2412-D8489Nordanalyt2025-Q199.386.30102.0Buyer-sourced1MARGINAL
AX-2025-018820QSC-2412-D8489Janoshik2025-Q199.555.64Buyer-sourced1MARGINAL
AX-2025-018821QSC-2412-D8489PeptideMeter2025-Q199.885.70Buyer-sourced1MARGINAL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik899.57, 99.29, 99.60, 99.81, 99.47, 99.81, 99.43, 99.5599.5630min+0.0099.56
Medutest299.93, 99.6899.8125min+0.0899.73
PeptideMeter499.48, 99.60, 99.93, 99.8899.7428min-0.0599.79
Nordanalyt299.62, 99.3899.5035min+0.0299.48

This lot contributes 6 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)99.2199.57divergence -0.39 pp vs batch median
Total impurities (% area)not stated0.43
Largest single impurity (% area)not stated0.24
Water (%)4.05.68
Counter-ion (%)3.08.40
Peptide content (%w/w)96.485.51
Endotoxin (EU/mg)not statednot determined
Method stated on certificateYEScolumn, gradient and wavelength given
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
acetylated N-terminus (+42 Da)16 / 160.230.03–0.47
des-Gly truncate (−57 Da)15 / 160.060.01–0.10
truncated (1-12)8 / 160.030.01–0.05
BPC-157 arginine-salt artefact8 / 160.080.04–0.14
[D-Val]-diastereomer7 / 160.080.04–0.10
pyroglutamate cyclisation (−17 Da)5 / 160.020.01–0.02
Section 7

What this rollup does not establish