Afamelanotide by laboratory
The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for Afamelanotide, with a class minimum gradient of 22 min, the method is a live explanation.
| Laboratory | Reports | Gradient | MS resolution | Median purity % | Published bias (pp) | Bias-adjusted | Method suitability |
|---|---|---|---|---|---|---|---|
| Janoshik | 29 | 30min | High | 99.20 | +0.00 | 99.20 | ADEQUATE |
| Nordanalyt | 8 | 35min | High | 99.24 | +0.02 | 99.22 | ADEQUATE |
| PeptideMeter | 6 n=6 | 28min | High | 99.80 | -0.05 | 99.85 | ADEQUATE |
| Medutest | 6 n=6 | 25min | Unit | 99.05 | +0.08 | 98.97 | ADEQUATE |
| VendorInvestigate | 4 n=4 | 32min | High | 99.35 | -0.11 | 99.46 | ADEQUATE |
| Kestrel | 0 | 15min | Unit | — | +0.24 | — | BELOW CLASS MINIMUM |