AssayIndex
Impurities & degradation

Isoaspartate

The rearranged product of deamidation via a succinimide intermediate. Mass-identical to aspartate-containing peptide.

Related terms

Deamidation
Conversion of asparagine to aspartate or glutamine to glutamate, +0.984 Da. A storage degradation route, accelerated above pH 7.
see also Isoaspartate
Aspartimide
A cyclic imide formed at an Asp-X motif, −18.011 Da. Hydrolyses to a mixture of α- and β-aspartyl peptides, the latter mass-identical to the parent.

Where this term appears

The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.