AssayIndex
Impurities & degradation

Diastereomer

A stereoisomer arising from inversion at one chiral centre. Same formula, same mass, same UV spectrum, often much less active. The impurity no mass spectrum finds.

Related terms

Epimerisation
Inversion of a single stereocentre during synthesis, typically during carboxyl activation. Produces a diastereomer.
Racemisation
Loss of stereochemical purity toward a 50:50 mixture. In stepwise peptide synthesis the practical concern is epimerisation at individual residues.
see also Epimerisation

Where this term appears

The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.