AssayIndex

AX-2026-043715

GHRP-6 · 5 mg declared · Bachem Holding (Suzhou) Co., Ltd. · lot BCH-2603-Y7240

FAILPURITY ONLY
Report ID
AX-2026-043715
Compound
GHRP-6
Compound class
Growth-hormone axis peptides
Supplier
BCH — Bachem Holding (Suzhou) Co., Ltd.
Batch / lot
BCH-2603-Y7240
Declared label claim
5mg
Laboratory
Nordanalyt Laboratories
Assay date
28 Apr 2026
Submitted
22 May 2026
Quarter
2026-Q2
Submitter
n.beaulieu
Sample provenance
Buyer-sourced
Section 1

Results

Measured against the index acceptance specification for the growth-hormone axis peptides class. A specification is a decision the index made; a result is a measurement. See where each threshold came from.

ParameterMethodResultUnitIndex spec
PurityRP-HPLC, 35 min gradient, 214 nm98.72% area≥ 99.0FAIL
Total impuritiesRP-HPLC, sum of reported peaks1.28% area≤ 1.0FAIL
Largest single impurityRP-HPLC — bis-oxidised Trp (+32 Da)0.82% area≤ 1.00PASS
Identitynot ordered on this submissionnot determinedrequired for VERIFIED statusNOT TESTED
Total peptide contentby difference from the gravimetric mass balance88.95%w/wNOT TESTED
Target-compound contenttotal peptide content × purity87.81%w/wNOT TESTED
Gross fill (as weighed)five-place balance, under nitrogen5.07mg5 mg declaredNOT TESTED
Recovered target peptidegross fill × target content4.452mg5 mg claimNOT TESTED
Recovery against label claimrecovered ÷ claim89.0%90.0 – 110.0FAIL
Water contentKarl Fischer, coulometric, duplicate5.15%≤ 9.0PASS
Counter-ion (acetate)anion-exchange ion chromatography5.07%≤ 12.0PASS
Residual solvent + inorganic residueestimated — see /methods/residual-solvents-q3c/0.83%NOT TESTED
Endotoxinkinetic chromogenic LAL0.46EU/mg≤ 5.0PASS
Sterilitynot ordered on this submissionnot determinedno growthNOT TESTED
Appearancevisual, diffuse light, black and white backgroundWhite cake, partially collapsedwhite to off-white intact cakeFAIL
Reconstitution clarityreconstituted per submitter procedureClear, colourless, no visible particulatesclear, no visible particulatesPASS
pH (reconstituted, 1 mg/mL)potentiometric, two-point calibration5.262.5 – 8.0PASS
Retention time (observed)RP-HPLC, 35 min gradient9.78min9.73 ± 0.25 (normalised)PASS
Peak asymmetry (10 % height)Ph. Eur. 2.2.461.060.80 – 1.50PASS
Plate count, main peakN = 5.54 (t/w½)²93,600≥ 20,000PASS
Resolution to nearest impurityvs [D-Trp]-epimer1.07no index criterionREPORTED
Section 2

Chromatogram and peak integration

The figure is drawn from the table. It is not an independent illustration — if a number in the table changed, the trace would change with it.

0347169411041213883 GHRP-69.78 min · 98.72 % 9.10 same trace · ×50 vertical expansion, baseline-corrected · main peak off-scale reporting threshold 0.05 % area 0510152025303540 Retention time (min) Response (mAU)
Figure 1. RP-HPLC trace, 35 min gradient, 214 nm. Drawn from the peak-integration table below: peak positions are the reported retention times, peak areas are the reported area percentages, peak widths follow the reported plate count of 93,600, and skew follows the reported asymmetry factor of 1.06. Baseline noise is seeded from the report ID and is illustrative. The lower panel is the same trace at a stated vertical expansion with the slow gradient drift subtracted, because at full scale a 0.82 % impurity against a 98.72 % main peak is a line two pixels tall; the main peak runs off-scale there by design.
#PeakRTArea (µV·s)% areaΔ mass (Da)
1GHRP-6 — main peak9.784,798,09898.72
2bis-oxidised Trp (+32 Da)9.1039,8550.82+31.990
3[D-Trp]-epimer9.6413,1230.270.000
4des-Lys (−128 Da)9.525,3460.11-128.095
5oxidised Trp (+16 Da)9.383,8880.08+15.995
Closure check — purity + Σ impurities 100.00CLOSES

Reporting threshold 0.05 % area. Peaks below it are not reported and are therefore excluded from the total, which overstates purity by their sum — see peak integration.

Section 4

Gravimetric mass balance

Water, counter-ion, residual and total peptide content are exhaustive and mutually exclusive categories. They must account for 100 % of the cake mass. The index closes this to within 0.02 pp and the build asserts it.

ComponentDetermination%w/w of cake
WaterKarl Fischer5.15
Counter-ion (acetate)ion chromatography5.07
Residual solvent + inorganic residueestimated0.83
Total peptide contentby difference88.95
Total100.00 CLOSES

Supplier certificate, as declared

The supplier's own figures for this lot, beside the independent measurement. Divergence is assessed against the batch median, not against this single report — see rule AX-R05.

FigureSupplier COAThis reportIndex note
Purity (% area)98.2698.72divergence -0.46 pp vs batch median
Total impurities (% area)not stated1.28
Largest single impurity (% area)not stated0.82
Water (%)2.95.15
Counter-ion (%)not stated5.07
Peptide content (%w/w)not stated88.95
Endotoxin (EU/mg)0.280.46
Method stated on certificateNOno method section — the result cannot be reconciled against any other
Section 5

Provenance and caveats

Where a sample came from changes the weight of the evidence. The index treats it as a first-class field.

Sample provenance
Buyer-sourced
Evidentiary weight
Strongest available evidence in this index.
Chain of custody
Domestic warehouse despatch → submitter (2–8 °C, 26 d) → laboratory (courier, cold pack, 11 d) → assay.
Assay date
28 Apr 2026
Submitted to the index
22 May 2026
Laboratory
Nordanalyt Laboratories, Uppsala, Sweden
Method basis
35 min gradient · high-resolution MS
Verification status
PURITY ONLY
Section 6

Annotations 3

Signed technical comments from index contributors. Not a discussion forum — annotations question or contextualise the result, and the data team replies where a reply is warranted.

des_gly
bis-oxidised Trp (+32 Da) at 0.82 % points at an incomplete coupling rather than at decomposition. Deletion sequences do not form in a vial; they form on a resin, and they are fixed by a double coupling rather than by a colder courier.
multiple_compare
Sixty-six compounds and twenty suppliers is a lot of cells. Some records will sit below specification by chance alone, and a single one is not a supplier finding. The per-compound table on the scorecard is the correct denominator.
lot_traceability
Lot BCH-2603-Y7240 on the vial matches the certificate that came with it. That is the check every buyer can do in ten seconds and most do not.
Section 7

Related records

Same batch — lot BCH-2603-Y7240 n=1

This is the only report on this lot. One report is not a batch characterisation.

Other recent GHRP-6 records in the index.
ReportSupplierLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-042438HJHJ-2603-R4071Janoshik2026-Q399.543.3994.1Buyer-sourced0PASS
AX-2026-042439HJHJ-2603-R4071Medutest2026-Q399.572.75Buyer-sourced0PASS
AX-2026-042437HJHJ-2603-R4071Janoshik2026-Q399.472.63Buyer-sourced0PASS
AX-2026-042435HJHJ-2603-R4071Nordanalyt2026-Q399.413.1799.7Buyer-sourced0PASS
AX-2026-042431HJHJ-2603-R4071PeptideMeter2026-Q399.062.97101.1Buyer-sourced0PASS
AX-2026-042427HJHJ-2603-R4071Janoshik2026-Q399.133.32Buyer-sourced0PASS
AX-2026-042433HJHJ-2603-R4071Janoshik2026-Q399.242.89102.4Buyer-sourced0PASS
AX-2026-042432HJHJ-2603-R4071Nordanalyt2026-Q399.473.2296.2Buyer-sourced0PASS
Other recent BCH records in the index.
ReportCompoundLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-043691BPC-157BCH-2603-L7768Janoshik2026-Q398.665.12Supplier-supplied1MARGINAL
AX-2026-043693BPC-157BCH-2603-L7768PeptideMeter2026-Q397.825.2194.9Buyer-sourced0FAIL
AX-2026-043686BPC-157BCH-2603-L7768VendorInvestigate2026-Q397.645.27Buyer-sourced0FAIL
AX-2026-043695BPC-157BCH-2603-L7768Janoshik2026-Q397.615.42Buyer-sourced0FAIL
AX-2026-043726N-Acetyl Semax AmideBCH-2602-E8475Janoshik2026-Q397.899.67104.2Buyer-sourced0FAIL
AX-2026-043688BPC-157BCH-2603-L7768Janoshik2026-Q397.945.56Buyer-sourced0FAIL
AX-2026-043658BPC-157BCH-2603-G6644Janoshik2026-Q398.454.37101.8Supplier-supplied0PASS
AX-2026-043692BPC-157BCH-2603-L7768VendorInvestigate2026-Q397.605.61Buyer-sourced0FAIL