AssayIndex

AX-2026-043668

GHRP-2 · 5 mg declared · Bachem Holding (Suzhou) Co., Ltd. · lot BCH-2508-M6766

FAILPURITY ONLY
Report ID
AX-2026-043668
Compound
GHRP-2
Compound class
Growth-hormone axis peptides
Supplier
BCH — Bachem Holding (Suzhou) Co., Ltd.
Batch / lot
BCH-2508-M6766
Declared label claim
5mg
Laboratory
PeptideMeter
Assay date
03 Mar 2026
Submitted
10 Mar 2026
Quarter
2026-Q1
Submitter
l.nwosu
Sample provenance
Buyer-sourced
Section 1

Results

Measured against the index acceptance specification for the growth-hormone axis peptides class. A specification is a decision the index made; a result is a measurement. See where each threshold came from.

ParameterMethodResultUnitIndex spec
PurityRP-HPLC, 28 min gradient, 214 nm98.75% area≥ 99.0FAIL
Total impuritiesRP-HPLC, sum of reported peaks1.25% area≤ 1.0FAIL
Largest single impurityRP-HPLC — oxidised Trp (+16 Da)0.60% area≤ 1.00PASS
Identitynot ordered on this submissionnot determinedrequired for VERIFIED statusNOT TESTED
Total peptide contentby difference from the gravimetric mass balance86.23%w/wNOT TESTED
Target-compound contenttotal peptide content × purity85.15%w/wNOT TESTED
Gross fill (as weighed)five-place balance, under nitrogen6.11mg5 mg declaredNOT TESTED
Recovered target peptidegross fill × target content5.203mg5 mg claimNOT TESTED
Recovery against label claimrecovered ÷ claim104.1%90.0 – 110.0PASS
Water contentKarl Fischer, coulometric, duplicate5.35%≤ 9.0PASS
Counter-ion (acetate)anion-exchange ion chromatography7.59%≤ 12.0PASS
Residual solvent + inorganic residueestimated — see /methods/residual-solvents-q3c/0.83%NOT TESTED
Endotoxinnot ordered on this submissionnot determined≤ 5.0NOT TESTED
Sterilitynot ordered on this submissionnot determinedno growthNOT TESTED
Appearancevisual, diffuse light, black and white backgroundOff-white lyophilised cake, intactwhite to off-white intact cakePASS
Reconstitution clarityreconstituted per submitter procedureClear, colourless, no visible particulatesclear, no visible particulatesPASS
pH (reconstituted, 1 mg/mL)potentiometric, two-point calibration5.852.5 – 8.0PASS
Retention time (observed)RP-HPLC, 28 min gradient8.39min8.50 ± 0.25 (normalised)PASS
Peak asymmetry (10 % height)Ph. Eur. 2.2.460.950.80 – 1.50PASS
Plate count, main peakN = 5.54 (t/w½)²56,674≥ 20,000PASS
Resolution to nearest impurityvs [D-2-Nal]-epimer0.90no index criterionREPORTED
Section 2

Chromatogram and peak integration

The figure is drawn from the table. It is not an independent illustration — if a number in the table changed, the trace would change with it.

033276653998013307 GHRP-28.39 min · 98.75 % 8.05 same trace · ×100 vertical expansion, baseline-corrected · main peak off-scale reporting threshold 0.05 % area 051015202530 Retention time (min) Response (mAU)
Figure 1. RP-HPLC trace, 28 min gradient, 214 nm. Drawn from the peak-integration table below: peak positions are the reported retention times, peak areas are the reported area percentages, peak widths follow the reported plate count of 56,674, and skew follows the reported asymmetry factor of 0.95. Baseline noise is seeded from the report ID and is illustrative. The lower panel is the same trace at a stated vertical expansion with the slow gradient drift subtracted, because at full scale a 0.60 % impurity against a 98.75 % main peak is a line two pixels tall; the main peak runs off-scale there by design.
#PeakRTArea (µV·s)% areaΔ mass (Da)
1GHRP-2 — main peak8.394,799,55698.75
2oxidised Trp (+16 Da)8.0529,1620.60+15.995
3des-Lys (−128 Da)8.1716,5250.34-128.095
4C-terminal free acid (+1 Da)8.548,7490.18+0.984
5[D-2-Nal]-epimer8.266,3180.130.000
Closure check — purity + Σ impurities 100.00CLOSES

Reporting threshold 0.05 % area. Peaks below it are not reported and are therefore excluded from the total, which overstates purity by their sum — see peak integration.

Section 4

Gravimetric mass balance

Water, counter-ion, residual and total peptide content are exhaustive and mutually exclusive categories. They must account for 100 % of the cake mass. The index closes this to within 0.02 pp and the build asserts it.

ComponentDetermination%w/w of cake
WaterKarl Fischer5.35
Counter-ion (acetate)ion chromatography7.59
Residual solvent + inorganic residueestimated0.83
Total peptide contentby difference86.23
Total100.00 CLOSES

Supplier certificate, as declared

The supplier's own figures for this lot, beside the independent measurement. Divergence is assessed against the batch median, not against this single report — see rule AX-R05.

FigureSupplier COAThis reportIndex note
Purity (% area)98.9398.75divergence +0.18 pp vs batch median
Total impurities (% area)not stated1.25
Largest single impurity (% area)not stated0.60
Water (%)4.75.35
Counter-ion (%)4.47.59
Peptide content (%w/w)99.486.23
Endotoxin (EU/mg)not statednot determined
Method stated on certificateYEScolumn, gradient and wavelength given
Section 5

Provenance and caveats

Where a sample came from changes the weight of the evidence. The index treats it as a first-class field.

Sample provenance
Buyer-sourced
Evidentiary weight
Strongest available evidence in this index.
Chain of custody
Retail purchase → third-party forwarder (33 d) → laboratory (courier, cold pack, 9 d) → assay.
Assay date
03 Mar 2026
Submitted to the index
10 Mar 2026
Laboratory
PeptideMeter, Tallinn, Estonia
Method basis
28 min gradient · high-resolution MS
Verification status
PURITY ONLY
Section 6

Annotations 4

Signed technical comments from index contributors. Not a discussion forum — annotations question or contextualise the result, and the data team replies where a reply is warranted.

gradient_25
Before treating 98.75 % as a process finding, check what it is being compared against. The index specification assumes the reference gradient; a figure taken on a different method is not automatically comparable to it.
iqr_watcher
One low result does not characterise a supplier and one high one does not either. The question is whether this lot sits in the left tail of a tight distribution or in the middle of a wide one, and the scorecard's IQR answers it.
buyer_sourced
Anyone can generate one of these. That is the argument the index makes on its submission page and it is the reason the dataset grows without any supplier's cooperation.
peak_integrator
Anyone comparing this purity figure against a result from a longer method should expect a difference of a few tenths in a predictable direction. The inter-lab page quantifies it per laboratory.
Section 7

Related records

Same batch — lot BCH-2508-M6766 n=9

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-043665BCH-2508-M6766Nordanalyt2026-Q198.735.3889.8Buyer-sourced2FAIL
AX-2026-043666BCH-2508-M6766Janoshik2026-Q198.665.67Supplier-supplied1FAIL
AX-2026-043667BCH-2508-M6766Medutest2026-Q199.105.32Supplier-supplied1MARGINAL
AX-2026-043669BCH-2508-M6766Janoshik2026-Q198.505.24100.9Buyer-sourced1FAIL
AX-2026-043670BCH-2508-M6766PeptideMeter2026-Q199.105.47106.8Supplier-supplied1MARGINAL
AX-2026-043671BCH-2508-M6766PeptideMeter2026-Q198.814.83Buyer-sourced1FAIL
AX-2026-043672BCH-2508-M6766Janoshik2026-Q198.616.2496.4Buyer-sourced1FAIL
AX-2026-043673BCH-2508-M6766PeptideMeter2026-Q199.265.69103.4Buyer-sourced1MARGINAL
Other recent GHRP-2 records in the index.
ReportSupplierLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-042471HJHJ-2602-W4961VendorInvestigate2026-Q299.031.69Buyer-sourced0PASS
AX-2026-042473HJHJ-2602-W4961Nordanalyt2026-Q299.081.28Buyer-sourced0PASS
AX-2026-042313HomopeptideHOMO-2602-E2105Janoshik2026-Q299.914.5190.4Buyer-sourced0PASS
AX-2026-042312HomopeptideHOMO-2602-E2105Medutest2026-Q299.444.16Buyer-sourced0PASS
AX-2026-042316HomopeptideHOMO-2602-E2105Janoshik2026-Q299.904.39103.7Buyer-sourced0PASS
AX-2026-042468HJHJ-2602-W4961Janoshik2026-Q299.211.22102.3Buyer-sourced0PASS
AX-2026-042472HJHJ-2602-W4961Medutest2026-Q299.111.73Buyer-sourced0PASS
AX-2026-042475HJHJ-2602-W4961Janoshik2026-Q299.121.46Buyer-sourced0PASS
Other recent BCH records in the index.
ReportCompoundLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-043691BPC-157BCH-2603-L7768Janoshik2026-Q398.665.12Supplier-supplied1MARGINAL
AX-2026-043693BPC-157BCH-2603-L7768PeptideMeter2026-Q397.825.2194.9Buyer-sourced0FAIL
AX-2026-043686BPC-157BCH-2603-L7768VendorInvestigate2026-Q397.645.27Buyer-sourced0FAIL
AX-2026-043695BPC-157BCH-2603-L7768Janoshik2026-Q397.615.42Buyer-sourced0FAIL
AX-2026-043726N-Acetyl Semax AmideBCH-2602-E8475Janoshik2026-Q397.899.67104.2Buyer-sourced0FAIL
AX-2026-043688BPC-157BCH-2603-L7768Janoshik2026-Q397.945.56Buyer-sourced0FAIL
AX-2026-043658BPC-157BCH-2603-G6644Janoshik2026-Q398.454.37101.8Supplier-supplied0PASS
AX-2026-043692BPC-157BCH-2603-L7768VendorInvestigate2026-Q397.605.61Buyer-sourced0FAIL