Epimerisation
Inversion of a single stereocentre during synthesis, typically during carboxyl activation. Produces a diastereomer.
Related terms
- Diastereomer
- A stereoisomer arising from inversion at one chiral centre. Same formula, same mass, same UV spectrum, often much less active. The impurity no mass spectrum finds.
- Racemisation
- Loss of stereochemical purity toward a 50:50 mixture. In stepwise peptide synthesis the practical concern is epimerisation at individual residues.
see also Epimerisation · Racemisation
see also Epimerisation
Where this term appears
The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.
- Assay report records — the term appears in result tables, peak tables and provenance blocks
- Method references — where the measurement behind the term is defined
- All 5 glossary terms beginning with E