AssayIndex
Chromatography

HILIC

Hydrophilic-interaction liquid chromatography. Polar stationary phase, high-organic mobile phase. Retains polar analytes that reverse phase cannot hold.

Related terms

Ion-pair chromatography
Adding an amphiphilic counter-ion to the mobile phase so a charged analyte forms a neutral pair with enough hydrophobic character to be retained on C18.
see also HILIC
Reverse-phase chromatography
Separation on a non-polar stationary phase, typically C18-bonded silica, with a polar mobile phase. Retains by hydrophobic interaction.
see also HILIC · C18

Where this term appears

The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.